Search results for "Corneal thickness"
showing 10 items of 14 documents
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus
2013
The author manuscript of this article is open access and is freely available online at PubMed Central
Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma
2014
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma, and variability in IOP might herald glaucomatous development or progression. We report the results of a genome-wide association study meta-analysis of 18 population cohorts from the International Glaucoma Genetics Consortium (IGGC), comprising 35,296 multi-ancestry participants for IOP. We confirm genetic association of known loci for IOP and primary open-angle glaucoma (POAG) and identify four new IOP-associated loci located on chromosome 3q25.31 within the FNDC3B gene (P = 4.19 x 10(-8) for rs6445055), two on chromosome 9 (P = 2.80 x 10(-11) for rs2472493 near ABCA1 and P = 6.39 x 10(-11) for rs8176693…
Corneal thickness differences between type 2 diabetes and non-diabetes subjects during preoperative laser surgery examination
2016
Aims To evaluate the differences in corneal thickness between type 2 diabetes subjects with HbA1c under 7.0% and non-diabetes subjects during their preoperative laser surgery examinations. Methods The mean of five consecutive corneal thickness measurements at the central and mid-peripheral cornea was obtained by means of noncontact scanning-slit corneal topography (Orbscan Topography System II; Orbscan, Inc., Salt Lake City, UT, USA) in 35 myopic non-insulin dependent type 2 diabetes subjects (17 males and 18 females) and 48 healthy myopic controls (23 males and 25 females). Results The corneal thickness values at the central and mid-peripheral cornea were significantly higher in the diabet…
Corneal thickness in children with growth hormone deficiency: The effect of GH treatment.
2014
Abstract OBJECTIVE: The eye represents a target site for GH action, although few data are available in patients with GH deficiency (GHD). Our aim was to evaluate central corneal thickness (CCT) and intraocular pressure (IOP) values in GHD children to assess the role played by GHD or GH treatment on these parameters. DESIGN: In 74 prepubertal GHD children (51M, 23F, aged 10.4±2.4years) we measured CCT and IOP before and after 12months of treatment. A baseline evaluation was also made in 50 healthy children matched for age, gender and body mass index. The study outcome considered CCT and IOP during treatment and their correlations with biochemical and auxological data. RESULTS: No difference …
Do Age and Sex Play a Role in the Intraocular Pressure Changes after Acrobatic Gymnastics?
2021
To evaluate the effects of an acrobatic gymnastics (AG) training session on intraocular pressure (IOP), a familiarization session was employed to confirm the participant’s suitability for the study. Forty-nine gymnasts (63.27% females, 18–40 years old) voluntarily agreed to participate. As age, sex, baseline IOP, and central corneal thickness (CCT) were considered as potential predictors of the IOP variations, in the second session measurements of the above parameters were taken before and after 90 min of AG. A mixed-factorial analysis of variance evaluated differences. Linear regression was conducted to potentially predict the IOP variation with the exercise. After the scheduled exercise, …
Reliability of manual segmentation of cornea, contact lens and tear film using a high-resolution OCT
2015
In this study, we aimed to evaluate the intra/inter-session and intra/inter-observer variability of manual segmentation of thickness of the pre-lens tear film, contact lens (CL), post-lens tear film, epithelium, bowman’s layer, stroma and the whole cornea and CLs with a flat and a steep fit, using a commercial high-resolution spectral domain optical coherence tomographer (OCT). Two different observers obtained three repeated measures in two separate sessions. A high correlation was found between the values obtained by the two different observers, except for the thinner layers, epithelium, and Bowman’s layer. Inter-observer analysis showed a high consistency in the measurements obtained by b…
Variations in central corneal thickness during the menstrual cycle in women.
2007
PURPOSE: We report changes in the central corneal thickness during various phases of the menstrual cycle. METHODS: We recruited 16 healthy women of reproductive age and measured the central corneal thickness at 3 points in their menstrual cycle, beginning on days 1 to 3 and again at ovulation and at the end of the cycle (days 27-32). Ovulation was determined with a test that determines the peak of luteinizing hormone in the urine. RESULTS: We found that the central cornea was thinnest at the beginning of the cycle (mean = 536 microm). Corneal thickness increased at ovulation (mean = 549 microm) and at the end of the cycle (mean = 559 microm). The difference in corneal thickness was statisti…
Orbscan Pachymetry: Differences between observers when carrying out measurements of the corneal thickness
2005
espanolObjetivo: Estudiar el espesor corneal y la variabilidad entre observadores de las mediciones del espesor corneal empleando paquimetria Orbscan. Metodos: Analizamos el espesor corneal central y paracentral de 30 sujetos (n=30) cuya edad oscilaba entre 19 y 38 anos (media 27,27 D.E. 5,25) con el Sistema Topografico Orbscan II (Orbscan, Inc., Salt Lake City, UT, USA). La media de cinco mediciones consecutivas del espesor corneal fue obtenida por dos diferentes observadores. Los resultados obtenidos por los dos observadores se compararon. Resultados: No se encontraron diferencias significativas entre los valores medios del espesor corneal de los observadores en la cornea central (p=0,749…
Radzenes biezuma un acs refrakcijas korelācija bērniem.
2020
Maģistra darbs ir uzrakstīts 46 lappusēm angļu valodā. Tas satur 19 attēlus, 9 tabulas, un 62 informācijas avotus. Šī darba mērķis ir izpētīt korelāciju starp radzenes biezumu un acs refrakciju 5-12 gadus veciem bērniem. Radzenes biezuma kartes un keratometrija tika mērīta, izmantojot Scheimpflug attēl veidošanas sistēmu Schwind Sirius. Keratometrija un refrakcija tika mērīta, izmantojot autokeratorefraktotonometru Topcon TRK-2P cikloplēģijā. Katram parametram tika veikti trīs mērījumi turpmākai analīzei. Šī pētījuma nolūkos tika analizētas 196 acis. Dalībniekiem ar hipermetropiju un hipermetropo astigmātismu novēroja lielākas radzenes biezuma vērtības centrā un radzenes perifērijā, atšķirī…